In 1893, after two years at the University of Nebraska, Lewis transferred to Harvard University, where he obtained his B. A friend of Nernst's, Wilhelm Palmær (Swedish), was a member of the Nobel Chemistry Committee.
There is evidence that he used the Nobel nominating and reporting procedures to block a Nobel Prize for Lewis in thermodynamics by nominating Lewis for the prize three times, and then using his position as a committee member to write negative reports.
Lewis Hall at Berkeley, built in 1948, is named in his honor.
Most of Lewis’ lasting interests originated during his Harvard years.
In two long and ambitious theoretical papers in 19, Lewis tried to provide a solution.
Lewis introduced the thermodynamic concept of activity and coined the term "fugacity".
Most chemists relied on the familiar thermodynamics of heat (enthalpy) of Berthelot, Ostwald, and Van’t Hoff, and the calorimetric school.
At Harvard, Lewis also wrote a theoretical paper on the thermodynamics of blackbody radiation in which he postulated that light has a pressure.In 1926, Lewis coined the term "photon" for the smallest unit of radiant energy. After Lewis' death, his children followed their father's career in chemistry. Additionally, the wing of the new Weymouth High School Chemistry department has been named in his honor.He was a brother in Alpha Chi Sigma, the professional chemistry fraternity. Lewis was born in 1875 and raised in Weymouth, Massachusetts, where there exists a street named for him, G. Lewis received his primary education at home from his parents, Frank Wesley Lewis, a lawyer of independent character, and Mary Burr White Lewis. in 1899 with a dissertation on electrochemical potentials.He later revealed that he had been discouraged from pursuing this idea by his older, more conservative colleagues, who were unaware that Wilhelm Wien and others were successfully pursuing the same line of thought.Lewis’ paper remained unpublished; but his interest in radiation and quantum theory, and (later) in relativity, sprang from this early, aborted effort.